What to Do When Erectile Dysfunction Drugs Don't Work

Erectile dysfunction is a very common condition that affects around 30 million men in the United States. If you have been prescribed a medication for erectile dysfunction and it doesn't seem to be working, it's best to contact your healthcare provider for help. The cause of erectile dysfunction may be due to an underlying health condition, such as problems with nerves, blood vessels, or hormones. If medications for erectile dysfunction don't work for you, it's important to talk to a healthcare provider about being evaluated for other factors that could be causing the problem.

The first-line treatment for erectile dysfunction is the use of oral medications called phosphodiesterase inhibitors (PDE5i). These medications are more commonly known as Viagra, Cialis, Levitra, Stayxn and Sandra. Oral medications for erectile dysfunction are an easy option for men to improve their stiffness and endurance during activity. However, men can often find that they are not responding to the medication.

In clinical trials, oral medications for erectile dysfunction have an overall efficacy of approximately 60-70%. In clinical practice, the failure rate of oral medication for erectile dysfunction can reach up to 50%, since patients may have more serious vascular conditions that hinder the drug's effectiveness. Viagra may lose its effectiveness over time due to changes in your body or changes in your health. If this happens, you can try switching to another drug in the same class (that is, another PDE5 inhibitor).

However, because Viagra works in a similar way to medications that contain nitrates, it's not recommended for men who take nitrates for heart disease or for those with other heart conditions.In a study, 69 percent of men who reported that their penile problems persisted even after taking first-line PDE5 inhibitor medications for erectile dysfunction made some mistakes when taking the pills. While this is not an FDA-approved drug use, the American Urological Association has included the use of sildenafil citrate in the treatment of premature ejaculation.These two medications work best on an empty stomach, so you should wait at least 2 to 3 hours after a full meal to take them. The International Index of Erectile Function (IIEF) is a questionnaire that can quantify the severity of erectile dysfunction.If your erectile dysfunction (ED) medications don't help you rise to the occasion, it doesn't necessarily mean you're out of luck. Some people are successful with “the little blue pill” (also known as Viagra) and discover that it is sufficient to treat their ED.

Drug use and erectile dysfunction may be related depending on the medications or drugs you take and how you take them.According to the Indianapolis Grey Clinic, which specializes in erectile dysfunction, 17% of men between 18 and 55 years old experience occasional impotence while 6% have regular erectile difficulties. The four PDE5 inhibitors are the only oral medications approved in the United States by the Food and Drug Administration to treat ED. In trials with patients with testosterone deficiency, treatment with testosterone undecanoate or enanthate improves the erectile response to vardenafil and tadalafil.

Bridget Lauby
Bridget Lauby

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